本研究主要探討安全氣候與工作壓力、工作敬業心間之關係，並利用健康促進活動認知做為調節變項，及驗證工作壓力在安全氣候與工作敬業心間之中介效果。本研究以具危害性物品運輸?職業駕駛為研究對象，問卷共回收356份有效問卷；並透過描述性統計分析、驗證性因素分析、相關分析、迴歸分析等統計方法探討變數間的關係。 本研究以複迴歸分析進行主要的假設驗證，經實證分析結果顯示如下：一、安全氣候對工作壓力具顯著負向影響。二、工作壓力對工作敬業心具顯著負向影響。三、安全氣候對工作敬業心具顯著的正向影響。四、工作壓力在安全氣候與工作敬業心間具部份中介效果。五、健康促進活動認知在工作壓力與工作敬業心間具調節效果 最後，依據研究結果，本研究提出結論與建議供後續研究參考。 This study focuses on the relationships among safety climate, work stress, and job engagement. Meanwhile, the mediating effect of work stress between safety climate and job engagement and the moderating effect of perceived health promotion activities between work stress and job engagement are explored in the study.In this study, a total of 356 valid questionnaires were collected. The statistical methods of descriptive statistical analysis, confirmatory factor analysis, correlation analysis, and multiple regression analysis were used to analyze the data.The empirical results of the study showed as follows.1. Safety climate has a significantly negative influence on work pressure.2. Work pressure has a significantly negative influence on job engagement.3. Safety climate has a significantly positive influence on job engagement.4. Work pressure has a partially mediating effect between safety climate and job engagement.5. Perceived health promotion activities have a moderating effect between work pressure and job engagement.Based on the results of the study, there are some concrete conclusions and suggestions provided as references in the future study.