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    Please use this identifier to cite or link to this item: http://ccur.lib.ccu.edu.tw/handle/A095B0000Q/537

    Title: 用於放射治療之多視角即時呼吸導引系統;Multiple View-Angle Real-Time Breathing Guidance System for Radiotherapy
    Authors: 陳欣喨;Chen, Hsin-Liang
    Contributors: 資訊工程研究所
    Keywords: 發光二極體目標定位;放射線治療;門控技術;呼吸控制;LED Marker Positioning;Radiation Therapy;Gating Method;Breath Control
    Date: 2016
    Issue Date: 2019-07-17
    Publisher: 資訊工程研究所
    Abstract: 衛福部 103 年公布惡性腫瘤已連續33年被列為國人的主要死因,治療惡性腫瘤常見的方法是放射線治療,使用高速電子撞擊金屬靶產生出的高能量X光照射惡性腫瘤,阻止其異常的生長速度達到治療效果。在放射治療過程中光束應該要集中在腫瘤上,然而有放療相關文獻提到病患的呼吸運動會改變內臟組織和惡性腫瘤的相對位置,導致放射治療的效果不如預期,最壞的情況可能是惡性腫瘤照射的劑量不足,而且還傷害到正常組織器官。為了避免預期外的腫瘤位移情況發生,臨床常見方法是利用呼吸門控的特性,為病患的呼吸深度設定一段門檻值,當深度達到門檻值才啟動放射光束治療,基於此機制我們提出一個低成本且能提高放射線治療效果的多視角影像呼吸導引系統,硬體上使用了數個常見的影像擷取裝置和一台電腦,搭配一套使用多種影像處理技術的系統,即時追蹤病患在放療過程中因呼吸運動產生的胸腹部形變,並與當初利用電腦斷層做腫瘤定位時的呼吸深度快照記錄做比較。兩個時間點的胸腹部形變曲線會重疊顯示在病患配戴的虛擬實境眼鏡上,病人可利用這些影像資訊控制當下的呼吸深淺以匹配腫瘤定位時的記錄,使腫瘤位置盡量與當初制定治療計畫所用的參考影像相對齊,進而減少正常組織或器官受到不必要的照射。
    According to the data of Ministry of Health and Welfare announced in 2014, malignant tumor has been the main cause of death for 33 consecutive years in Taiwan. A common treatment of malignant tumors is radiation therapy, which uses high-energy radiation beam to stop tumor growth and achieve therapeutic effect. The radiation beam should stay focusing on the malignancy during radiotherapy. However, previous studies showed that patients' respiratory movements alter the relative position between the visceral tissue and malignancy, resulting in less outcomes and extra damages.In order to avoid the occurrence of malignant tumor displacement, the common clinical solution is to set a threshold for the depth of patient's breath, and start the radiation beam illumination only when such depth reaches the threshold. Based on this mechanism we propose a “multi-perspective video-based breath guidance system”, which is low-cost and can improve the efficacy of radiation therapy. The hardware part includes several common imaging devices and a computer, along with a system software that includes a variety of image processing algorithms. This system can immediately track the thorax and abdomen deformations caused by respiratory movements in real time during radiotherapy, and compare with the original snapshot record of respiration depth when computer tomography was taken to locate the tumor. The thoracic and abdominal deformation curves at the two timing will be overlaid and projected on the patient's virtual reality headset. This information can be used to control the depth of the current breath to align with the one recorded during CT imaging, and reduce the damage of the normal tissue or organ from unnecessary irradiation.
    Appears in Collections:[資訊工程學系] 學位論文

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